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1

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, Mitsuhiro, Houten, Sander M., Mataki, Chikage, Christoffolete, Marcelo A., Kim, Brian W., Sato, Hiroyuki, Messaddeq, Nadia, Harney, John W., Ezaki, Osamu, Kodama, Tatsuhiko

Journal:

Year:

2006

Language:

english

File:

PDF, 523 KB

english, 2006

2

Peroxisome proliferator-activated receptor-γ: too much of a good thing causes harm

Cock, Terrie-Anne, Houten, Sander M., Auwerx, Johan

Journal:

Year:

2004

Language:

english

File:

PDF, 849 KB

english, 2004

3

Effects of Insulin on Ketogenesis Following Fasting in Lean and Obese Men

Maarten R. Soeters, Hans P. Sauerwein, Linda Faas, Martijn Smeenge, Marinus Duran, Ronald J. Wanders, An F. Ruiter, Mariëtte T. Ackermans, Eric Fliers, Sander M. Houten, Mireille J. Serlie

Journal:

Year:

2009

Language:

english

File:

PDF, 172 KB

english, 2009

4

Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is deficient

Violante, Sara, IJlst, Lodewijk, te Brinke, Heleen, Koster, Janet, Tavares de Almeida, Isabel, Wanders, Ronald J.A., Ventura, Fátima V., Houten, Sander M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2013

Language:

english

File:

PDF, 1.30 MB

english, 2013

5

Genetic basis of hyperlysinemia

Sander M Houten, Heleen te Brinke, Simone Denis…

Journal:

Orphanet Journal of Rare Diseases

Year:

2013

Language:

english

File:

PDF, 246 KB

english, 2013

6

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population

Wu, Yibo, Williams, Evan G., Dubuis, Sébastien, Mottis, Adrienne, Jovaisaite, Virginija, Houten, Sander M., Argmann, Carmen A., Faridi, Pouya, Wolski, Witold, Kutalik, Zoltán, Zamboni, Nicola, Auwerx,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.67 MB

english, 2014

7

A Mitochondrial Expatriate: Nuclear Pyruvate Dehydrogenase

de Boer, Vincent C.J., Houten, Sander M.

Journal:

Year:

2014

Language:

english

File:

PDF, 300 KB

english, 2014

8

Nasopharyngeal carriage of Streptococcus pneumoniae and other bacteria in the 7th year after implementation of the pneumococcal conjugate vaccine in the Netherlands

Bosch, Astrid A.T.M., van Houten, Marlies A., Bruin, Jacob P., Wijmenga-Monsuur, Alienke J., Trzciński, Krzysztof, Bogaert, Debby, Rots, Nynke Y., Sanders, Elisabeth A.M.

Journal:

Year:

2016

Language:

english

File:

PDF, 759 KB

english, 2016

9

Molecular surveillance of nasopharyngeal carriage of Streptococcus pneumoniae in children vaccinated with conjugated polysaccharide pneumococcal vaccines

Wyllie, Anne L., Wijmenga-Monsuur, Alienke J., van Houten, Marlies A., Bosch, Astrid A. T. M., Groot, James A., van Engelsdorp Gastelaars, Jody, Bruin, Jacob P., Bogaert, Debby, Rots, Nynke Y., Sander

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 553 KB

english, 2016

10

Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

Yang, Jialiang, Peng, Shouneng, Zhang, Bin, Houten, Sander, Schadt, Eric, Zhu, Jun, Suh, Yousin, Tu, Zhidong

Journal:

Year:

2019

Language:

english

File:

PDF, 1.93 MB

english, 2019

11

Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases

Yang, Jialiang, Peng, Shouneng, Zhang, Bin, Houten, Sander, Schadt, Eric, Zhu, Jun, Suh, Yousin, Tu, Zhidong

Journal:

Year:

2019

File:

PDF, 1.93 MB

2019

12

Metabolic interactions between peroxisomes and mitochondria with a special focus on acylcarnitine metabolism

Houten, Sander M., Wanders, Ronald J.A., Ranea-Robles, Pablo

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2020

File:

PDF, 777 KB

2020

13

Lack of isoprenoid products raises ex vivo interleukin-1β secretion in hyperimmunoglobulinemia D and periodic fever syndrome

Joost Frenkel, Ger T. Rijkers, Saskia H. L. Mandey, Sandra W. M. Buurman, Sander M. Houten, Ronald J. A. Wanders, Hans R. Waterham, Wietse Kuis

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

14

Manipulation of isoprenoid biosynthesis as a possible therapeutic option in mevalonate kinase deficiency

Marit S. Schneiders, Sander M. Houten, Marjolein Turkenburg, Ronald J. A. Wanders, Hans R. Waterham

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 170 KB

english, 2006

15

Critical assessment of human metabolic pathway databases: a stepping stone for future integration

Miranda D Stobbe, Sander M Houten, Gerbert A Jansen, Antoine HC van Kampen, Perry D Moerland

Journal:

BMC Systems Biology

Year:

2011

Language:

english

File:

PDF, 753 KB

english, 2011

16

A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

Sander Michel Houten, Ronald J. A. Wanders

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 390 KB

english, 2010

17

The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow-up analysis of positive neonatal screening results

Ronald J. A. Wanders, Jos P. N. Ruiter, Lodewijk IJlst, Hans R. Waterham, Sander M. Houten

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

18

10.1038/9691

Waterham, Hans R., Poll-The, Bwee Tien, Houten, Sander M., Kuis, Wietse, Duran, Marinus, de Koning, Tom J., van Royen-Kerkhof, Annet, Romeijn, Gerrit J., Frenkel, Joost, Dorland, Lambertus, de Barse,

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 104 KB

english, 1999

19

Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism

Mary-Elizabeth Patti, Sander M. Houten, Antonio C. Bianco, Raquel Bernier, P. Reed Larsen, Jens J. Holst, Michael K. Badman, Eleftheria Maratos-Flier, Edward C. Mun, Jussi Pihlajamaki, Johan Auwerx, A

Journal:

Year:

2009

Language:

english

File:

PDF, 541 KB

english, 2009

20

The Effects of Long- or Medium-Chain Fat Diets on Glucose Tolerance and Myocellular Content of Lipid Intermediates in Rats

Johan De Vogel-van den Bosch, Joris Hoeks, Silvie Timmers, Sander M. Houten, Paul J. van Dijk, Wendy Boon, Denis van Beurden, Gert Schaart, Sander Kersten, Peter J. Voshol, Ronald J.A. Wanders, Matthi

Journal:

Year:

2011

Language:

english

File:

PDF, 217 KB

english, 2011

21

Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome

Houten, Sander M, Koster, Janet, Romeijn, Gerrit-Jan, Frenkel, Joost, Di Rocco, Maja, Caruso, Ubaldo, Landrieu, Pierre, Kelley, Richard I, Kuis, Wietse, Poll-The, Bwee Tien

Journal:

European Journal of Human Genetics

Year:

2001

Language:

english

File:

PDF, 150 KB

english, 2001

22

Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome

Houten, Sander M, Koster, Janet, Romeijn, Gerrit-Jan, Frenkel, Joost, Di Rocco, Maja, Caruso, Ubaldo, Landrieu, Pierre, Kelley, Richard I, Kuis, Wietse, Poll-The, Bwee Tien

Journal:

European Journal of Human Genetics

Year:

2001

Language:

english

File:

PDF, 31 KB

english, 2001

23

Carrier frequency of the V377I (1129G>A) MVK mutation, associated with Hyper-IgD and periodic fever syndrome, in the Netherlands

Houten, Sander M, van Woerden, Christiaan S, Wijburg, Frits A, Wanders, Ronald J A, Waterham, Hans R

Journal:

European Journal of Human Genetics

Year:

2003

Language:

english

File:

PDF, 90 KB

english, 2003

24

Endocrine functions of bile acids

Houten, Sander M, Watanabe, Mitsuhiro, Auwerx, Johan

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

25

Peroxisomes and bile acid biosynthesis

Sacha Ferdinandusse, Sander M. Houten

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2006

Language:

english

File:

PDF, 504 KB

english, 2006

26

Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation

Mirjam Langeveld, Sjoerd A.A. van den Berg, Nora Bijl, Silvia Bijland, Cindy P. van Roomen, Judith H. Houben-Weerts, Roelof Ottenhoff, Sander M. Houten, Ko Willems van Dijk, Johannes A. Romijn, Albert

Journal:

Year:

2012

Language:

english

File:

PDF, 434 KB

english, 2012

27

Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite

Maarten R. Soeters, Mireille J. Serlie, Hans P. Sauerwein, Marinus Duran, Jos P. Ruiter, Willem Kulik, Mariëtte T. Ackermans, Paul E. Minkler, Charles L. Hoppel, Ronald J.A. Wanders, Sander M. Houten

Journal:

Year:

2012

Language:

english

File:

PDF, 510 KB

english, 2012

28

Meeting Report: EU–US Workshop on Molecular Signatures of DNA damage-induced Stress Responses: Cortona, Italy, 26–30 September 2003

Miriam Sander, Christian Desaintes, Richard Pelroy, Wouter Ferro, Bennett Van Houten, Sally Amundson, Alan Lehmann, Leon Mullenders, Susanna-Assunta Sansone, Peter Stambrook, Bert van Zeeland, Harry V

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2004

Language:

english

File:

PDF, 1.84 MB

english, 2004

29

Second EU-US workshop on systems level understanding of DNA damage responses

Miriam Sander, Christian Desaintes, Wouter Ferro, Leon Mullenders, Richard Pelroy, Bennett Van Houten, Harry Vrieling, Susan Wallace

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 1.40 MB

english, 2006

30

3rd US–EU Workshop: Systems level understanding of DNA damage responses

Miriam Sander, Thomas J. Begley, Christian Desaintes, Anne-Claude Gavin, Richard Pelroy, Joris Pothof, Yosef Shiloh, Dik van Gent, Ben Van Houten, Michael Yaffe, Leon Mullenders

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

31

Proceedings of a workshop on DNA adducts: Biological significance and applications to risk assessment Washington, DC, April 13–14, 2004

Miriam Sander, Jean Cadet, Daniel A. Casciano, Sheila M. Galloway, Lawrence J. Marnett, Raymond F. Novak, Syril D. Pettit, R. Julian Preston, Julie A. Skare, Gary M. Williams, Bennett Van Houten, B. B

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 643 KB

english, 2005

32

Nonorthologous Gene Displacement of Phosphomevalonate Kinase

Sander M Houten, Hans R Waterham

Journal:

Molecular Genetics and Metabolism

Year:

2001

Language:

english

File:

PDF, 60 KB

english, 2001

33

Mitochondrial long chain fatty acid β-oxidation in man and mouse

Malika Chegary, Heleen te Brinke, Jos P.N. Ruiter, Frits A. Wijburg, Maria S.K. Stoll, Paul E. Minkler, Michel van Weeghel, Horst Schulz, Charles L. Hoppel, Ronald J.A. Wanders, Sander M. Houten

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 1.14 MB

english, 2009

34

Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats

Jolita Ciapaite, Nicole M. van den Broek, Heleen te Brinke, Klaas Nicolay, Jeroen A. Jeneson, Sander M. Houten, Jeanine J. Prompers

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 1.39 MB

english, 2011

35

PGC-1α: Turbocharging mitochondria

Sander M. Houten, Johan Auwerx

Journal:

Year:

2004

Language:

english

File:

PDF, 132 KB

english, 2004

36

New Driver for Lipid Synthesis

Sander M. Houten, Carmen A. Argmann

Journal:

Year:

2011

Language:

english

File:

PDF, 380 KB

english, 2011

37

Homing in on bile acid physiology

Sander M. Houten

Journal:

Cell Metabolism

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

38

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

Jérôme N. Feige, Marie Lagouge, Carles Canto, Axelle Strehle, Sander M. Houten, Jill C. Milne, Philip D. Lambert, Chikage Mataki, Peter J. Elliott, Johan Auwerx

Journal:

Cell Metabolism

Year:

2008

Language:

english

File:

PDF, 1.18 MB

english, 2008

39

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

Jérôme N. Feige, Marie Lagouge, Carles Canto, Axelle Strehle, Sander M. Houten, Jill C. Milne, Philip D. Lambert, Chikage Mataki, Peter J. Elliott, Johan Auwerx

Journal:

Cell Metabolism

Year:

2009

File:

PDF, 39 KB

2009

40

Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Complex I

Jessica Nouws, Leo Nijtmans, Sander M. Houten, Mariël van den Brand, Martijn Huynen, Hanka Venselaar, Saskia Hoefs, Jolein Gloerich, Jonathan Kronick, Timothy Hutchin, Peter Willems, Richard Rodenburg

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 1.60 MB

english, 2010

41

PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

Péter Bai, Carles Canto, Attila Brunyánszki, Aline Huber, Magdolna Szántó, Yana Cen, Hiroyasu Yamamoto, Sander M. Houten, Borbala Kiss, Hugues Oudart, Pál Gergely, Josiane Menissier-de Murcia, Valérie

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 933 KB

english, 2011

42

Integrating multiple views of the cell: DNA repair jumps to higher level at Stowe workshop

Miriam Sander, Bennett Van Houten

Journal:

Year:

2006

Language:

english

File:

PDF, 235 KB

english, 2006

43

A liver revival featuring bile acids

Sander M. Houten

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

44

Enhanced memory B-cell immune responses after a second acellular pertussis booster vaccination in children 9 years of age

Lotte H. Hendrikx, Mariet K. Felderhof, Kemal Öztürk, Lia G.H. de Rond, Marlies A. van Houten, Elisabeth A.M. Sanders, Guy A.M. Berbers, Anne-Marie Buisman

Journal:

Year:

2011

Language:

english

File:

PDF, 780 KB

english, 2011

45

Characterization of l-aminocarnitine, an inhibitor of fatty acid oxidation

Malika Chegary, Heleen te Brinke, Mirjam Doolaard, Lodewijk IJlst, Frits A. Wijburg, Ronald J.A. Wanders, Sander M. Houten

Journal:

Molecular Genetics and Metabolism

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

46

Biochemical and genetic aspects of mevalonate kinase and its deficiency

Sander M Houten, Ronald J.A Wanders, Hans R Waterham

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2000

Language:

english

File:

PDF, 438 KB

english, 2000

47

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

Watanabe, Mitsuhiro, Houten, Sander M., Wang, Li, Moschetta, Antonio, Mangelsdorf, David J., Heyman, Richard A., Moore, David D., Auwerx, Johan

Journal:

Journal of Clinical Investigation

Year:

2004

Language:

english

File:

PDF, 641 KB

english, 2004

48

Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibroblasts by inhibiting fatty acid elongation

Engelen, Marc, Schackmann, Martin J. A., Ofman, Rob, Sanders, Robert-Jan, Dijkstra, Inge M. E., Houten, Sander M., Fourcade, Stéphane, Pujol, Aurora, Poll-The, Bwee Tien, Wanders, Ronald J. A., Kemp,

Journal:

Journal of Inherited Metabolic Disease

Year:

2012

Language:

english

File:

PDF, 724 KB

english, 2012

49

Carnitine supplementation attenuates myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice

Bakermans, Adrianus J., Weeghel, Michel, Denis, Simone, Nicolay, Klaas, Prompers, Jeanine J., Houten, Sander M.

Journal:

Journal of Inherited Metabolic Disease

Year:

2013

Language:

english

File:

PDF, 465 KB

english, 2013

50

Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid and branched-chain amino acid metabolism

Violante, Sara, IJlst, Lodewijk, Ruiter, Jos, Koster, Janet, van Lenthe, Henk, Duran, Marinus, de Almeida, Isabel Tavares, Wanders, Ronald J.A., Houten, Sander M., Ventura, Fátima V.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 668 KB

english, 2013